neo U-β-Carotene
9-cis-β-Carotene
CAS: 13312-52-2
Molecular Formula: C40H56
neo U-β-Carotene - Names and Identifiers
| Name | 9-cis-β-Carotene |
| Synonyms | (9Z)-β-Carotene neo U-β-Carotene 9-cis-β-Carotene Neo-β-carotene U (9Z)-β,β-Carotene (9Z)-beta-Carotene |
| CAS | 13312-52-2 |
neo U-β-Carotene - Physico-chemical Properties
| Molecular Formula | C40H56 |
| Molar Mass | 536.87 |
| Density | 0.941±0.06 g/cm3(Predicted) |
| Boling Point | 654.7±22.0 °C(Predicted) |
| BRN | 3227021 |
| Storage Condition | -20°C |
| In vitro study | 9-cis-β-Carotene (1 μM; 18 hours) formulates with the Miglyol 810 and the“antioxidant mix” is incubated to eye cups. The eye cups are isolated from the neuro-retina attached to the underlying RPE tissue fromRPE65rd12 mouse. It prevents S- and M-cones degeneration and leads to over 2- and 9- fold higher m-opsin and s-opsin positive staining compares to the control group. |
| In vivo study | In a mouse model of retinoid cycle defect, RPE65rd12. Mice with an extract of Dunaliella Bardawil algae rich in 9-cis-β-Carotene (9CBC) rescues retinal function and preserves cone structure by oral administration. |
neo U-β-Carotene - Risk and Safety
| WGK Germany | 3 |
neo U-β-Carotene - References
| biological activity | 9-cis-β-Carotene, a precursor of the retina, consists of β-carotene oxygenase 1 (BCMO1). Cleavage produced 9-cis-retinal. 9-cis-β-cartene inhibits retinal photoreceptor degeneration and helps restore retinal function in animal models. 9-cis-β-cartene has potential for the Study of congenital stationary night blindness. |
Last Update：2024-04-09 21:04:16
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